Inani lehlabathi losulelo kunye nokufa liqhubekile nokunyuka ukusukela oko kwaqala ubhubhani we-COVID-19.Ukusukela ngoSeptemba ka-2021, inani lokufa kwabantu kwihlabathi liphela ukusuka kwi-COVID-19 lidlule kwi-4.5 yezigidi, kunye namatyala angaphezu kwezigidi ezingama-222.
I-COVID-19 inobuzaza, kwaye asinako ukuphumla.Ukufunyaniswa kwangethuba, ukunika ingxelo kwangethuba, ukubekwa wedwa kwangethuba kunye nonyango lwakwangoko luyimfuneko ukunqumla ngokukhawuleza indlela yosulelo lwentsholongwane.
Ke ungayibhaqa njani iNtsholongwane yeCoronavirus?
Ukufunyaniswa kwe-COVID-19 nucleic acid kuvavanyo kunye nokuvavanywa kwamatyala aqinisekisiweyo e-COVID-19, amatyala ekurhaneleka ukuba yi-COVID-19 kunye nabantu abangenazimpawu zosuleleko ngeendlela zaselabhoratri.
1. I-Fluorescence indlela ye-PCR yexesha langempela
Indlela ye-PCR ibhekisa kwi-polymerase chain reaction, ethi inyuse ngokumangalisayo iimali ezincinci zeDNA.Ukufumana inoveli iCoronavirus, njengenoveli iCoronavirus yintsholongwane ye-RNA, i-RNA yentsholongwane kufuneka ikhutshelwe umva kwi-DNA ngaphambi kokufunyanwa kwe-PCR.
Umgaqo wokufumanisa i-PCR ye-fluorescence kukuba: kunye nenkqubela phambili ye-PCR, iimveliso zokusabela ziqhubeka ziqokelela, kunye nobukhulu besignali ye-fluorescence nabo banda ngokulinganayo.Ekugqibeleni, ijika le-fluorescence amplification lifunyenwe ngokubeka iliso kwinguqu yobuninzi bemveliso ngokutshintshwa kwe-fluorescence intensity.Le yeyona ndlela okwangoku isetyenziswa kakhulu kwinoveli yovavanyo lwe-coronavirus nucleic acid.
Nangona kunjalo, iintsholongwane ze-RNA zonakaliswa ngokulula ukuba azigcinwanga kakuhle okanye azithunyelwanga ukuba zihlolwe kwangethuba.Ke ngoko, emva kokufumana iisampulu zezigulane, kufuneka zigcinwe ngendlela esemgangathweni kwaye zivavanywe ngokukhawuleza.Ngaphandle koko, kunokukhokelela kwiziphumo zovavanyo ezingachanekanga.
Iityhubhu zesampulu zentsholongwane (Isetyenziselwa ukuqokelela, ukuthuthwa kunye nokugcinwa kweesampulu zentsholongwane ye-DNA/RNA.)
2. Iprobe edityanisiweyo ye-anchored polymerization indlela yokulandelelana
Olu vavanyo ikakhulu lusebenzisa izixhobo ezikhethekileyo zokubona ulandelelwano lwemfuza oluthwalwa yi-DNA nanospheres ekulandeleleni izilayidi.
Uvakalelo lolu vavanyo luphezulu, kwaye akulula ukuphosakela ukuxilongwa, kodwa iziphumo zichaphazeleka ngokulula ngezinto ezahlukeneyo kwaye azichanekanga.
3. Indlela yechip yokukhulisa iThermostatic
Umgaqo wokufumanisa usekelwe kwindibaniselwano ehambelanayo ye-nucleic acids phakathi kokuphuhliswa kwendlela yokufumanisa, ingasetyenziselwa ukulinganisa umgangatho okanye ubungakanani be-nucleic acids emzimbeni wezinto eziphilayo.
4. Ukufunyanwa kwe-antibody yentsholongwane
Ii-antibody reagents zisetyenziselwa ukukhangela izilwa-buhlungu ze-IgM okanye ze-IgG eziveliswa ngumzimba womntu emva kokuba intsholongwane ingene emzimbeni.Amajoni e-IgM avela kwangethuba kwaye amajoni e-IgG avela kamva.
5. Indlela yegolide yeColloidal
Indlela yegolide ye-Colloidal kukusebenzisa iphepha lovavanyo lwegolide ye-colloidal ukubhaqa, edla ngokuthiwa ngoku khawuleza iphepha lovavanyo.Olu hlobo loviwo lukwimizuzu eyi-10 ~ 15 okanye ngokwesiqhelo, lunokufumana iziphumo zokubhaqa.
6. I-Chemiluminescence yamasuntswana magnetic
I-Chemiluminescence yi-immunoassay ebuthathaka kakhulu enokuthi isetyenziswe ukumisela i-antigenicity yezinto.Indlela ye-magnetic particle chemiluminescence isekelwe ekubhaqweni kwe-chemiluminescence, yongeza i-nanoparticles yamagnetic, ukwenzela ukuba ukufumanisa kunovakalelo oluphezulu kunye nesantya sokufumanisa ngokukhawuleza.
Uvavanyo lwe-COVID-19 nucleic acid ye-VS yovavanyo lwe-antibody, yeyiphi onokuyikhetha?
Iimvavanyo ze-Nucleic acid isekuphela kovavanyo olusetyenziswayo ukuqinisekisa usulelo lweNoveli yekoronavirus. Kwiimeko ekurhanelwa ukuba kukho inoveli yovavanyo lwe-coronavirus nucleic acid negative, uvavanyo lwe-antibody lunokusetyenziswa njengesalathisi sovavanyo olongezelelweyo.
Inoveli yeCoronavirus(2019-nCoV) iNucleic Acid Detection Kit (Fluorescence PCR Method), ukucocwa kwe-Nucleic acid yeesampulu ezingama-32 kunokugqityezelwa kwimizuzu nje engama-20.
Ixesha lokwenyani leFluorescence Quantitative PCR Analyzer(iisampulu ezili-16, iisampulu ezingama-96)
Ixesha lokuposa: Sep-13-2021
